Ketoconazole 2% Shampoo is indicated for the treatment and prophylaxis of infections associated with the yeast Malassezia (formerly known as Pityrosporum), such as tinea versicolor (focal), seborrheic dermatitis and inflammatory diseases. capillaries (dandruff).
Ketoconazole 2% Shampoo is a broad spectrum imidazoledioxolane, a synthetic antifungal agent, which inhibits the in vitro growth of the following common fungi and skin fungi by altering the permeability of the cell membrane: Dermatophytes: Trichophyton rubrum, T. mentagrophytes, T. tonsils, Microsporum canis, M. audouini, M. gypseum and Epidermophyton floccosum; yeasts: Candida albicans, Malassezia ovale (Pityrosporum ovale) and C. tropicalize; and the organism that causes ringworm, Malassezia furfur (Pityrosporum orbiculare).
No information was found for the Shampoo form of Ketoconazole.
Contraindicated in patients with known hypersensitivity to ketoconazole.
Topical treatment with 2% ketoconazole shampoo is generally well tolerated. As with other shampoos, a local burning sensation, itching, or contact dermatitis (due to irritation or allergy) may occur on exposed areas of skin. Dry and oily hair has rarely been reported with the use of 2% ketoconazole shampoo.
In patients already on prolonged treatment with topical corticosteroids, corticosteroid therapy should be discontinued gradually over a period of 2 to 3 weeks, with concomitant use of 2% ketoconazole shampoo, in order to prevent any side effects that may occur. Excessive hair loss is usually associated with seborrheic dermatitis and dandruff, and has rarely been reported with the use of 2% ketoconazole shampoo. Avoid eye contact. If the shampoo gets into the eyes, they should be rinsed with water.
Since ketoconazole is not absorbed through the skin after application, pregnancy and lactation are not contraindications to the use of ketoconazole 2% shampoo.
Store in a cool and dry place, protected from light.
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